Top 5 Takeaways Continued incidence but decreasing trend of MIS-C: While the incidence of Multisystem Inflammatory Syndrome in Children (MIS-C) has decreased significantly from its peak early in the COVID-19

Top 5 Takeaways Significant Global Progress: From 2016 to 2020, global coverage with the third dose of hepatitis B vaccine remained stable while coverage with the hepatitis B birth dose

Top 5 Takeaways Significant Increase in Unsupervised Melatonin Ingestions: Approximately 11,000 emergency department (ED) visits for unsupervised melatonin ingestion by infants and young children occurred during 2019–2022, making up about

Top 5 Takeaways Significant Increase in Intracranial Infections: During the first two years of the COVID-19 pandemic, an increase in pediatric intracranial infections was observed, with cases often diagnosed during

Top 5 Takeaways Surge in Pediatric COVID-19 Cases: During the 2021–22 school year, New York reported a total of 702,686 COVID-19 cases among children aged 5–17, with a significant increase

Top 5 Takeaways Similar Adverse Reaction Frequencies: Children aged 5–11 years reported local and systemic reactions to the Pfizer-BioNTech COVID-19 vaccine booster dose with similar frequency as after the second

Top 5 Takeaways Increased HPV Vaccination: In 2021, there was an increase in HPV vaccination coverage among adolescents aged 13–17 years, with 76.9% having received at least one dose and

Top 5 Takeaways Widespread Vaccine Safety in Young Children: Among children aged 6 months–5 years, COVID-19 mRNA vaccines (Pfizer-BioNTech and Moderna) have shown a safety profile with primarily mild to

Top 5 Takeaways Decline in Vaccination Intent and Confidence Over 3 Months: Parental intent to vaccinate children under 5 against COVID-19 and confidence in vaccine safety and effectiveness decreased within