Top 5 Takeaways Reduced Reactions Post-Booster: Immunocompromised individuals aged ≥12 years reported fewer local and systemic reactions after the fourth dose (mRNA booster) compared to after the third dose of

Top 5 Takeaways Vaccine Effectiveness (VE) varies with dose number and Omicron sublineage. VE was generally lower during the Omicron BA.2/BA.2.12.1 period compared to the BA.1 period. A third dose

Top 5 Takeaways Reduction in Adverse Reactions: Among adults aged ≥50 years, adverse reactions were less frequent following a second mRNA COVID-19 booster dose compared to the first booster dose.