Top 5 Takeaways Overall Difficulty: In 2020, 12.3% of adults aged ≥18 years reported some difficulty hearing even when using a hearing aid, and 1.5% had a lot of difficulty

Top 5 Takeaways High Vaccine Effectiveness: Receiving 2 or 3 doses of an mRNA COVID-19 vaccine was associated with a 90% reduction in risk for COVID-19–associated invasive mechanical ventilation (IMV)

Top 5 Takeaways Higher Hospitalization Rates During Omicron: Weekly COVID-19–associated hospitalization rates peaked at 38.4 per 100,000 adults during Omicron predominance, compared to 15.5 during Delta predominance. Impact of Vaccination

Top 5 Takeaways Vaccine Effectiveness (VE) Variability: VE against COVID-19–associated emergency department/urgent care visits was 24% after 1 Janssen dose, 54% after 2 Janssen doses, 79% after 1 Janssen/1 mRNA

Top 5 Takeaways Prevalence of Developmental Disabilities: Approximately 17.3% of U.S. children and adolescents aged 3–17 years had developmental disabilities (DDs) during 2014–2018. Increased Health Service Use: Children with DDs