Top 5 Takeaways Lower Non-COVID-19 Mortality: COVID-19 vaccine recipients had lower rates of non–COVID-19 mortality compared to unvaccinated persons. Adjusted Relative Risk: The adjusted relative risk (aRR) of non–COVID-19 mortality

Top 5 Takeaways Delta Variant Predominance: The Delta variant became the predominant SARS-CoV-2 strain in the U.S. by mid-June 2021, leading to increased COVID-19-associated hospitalizations. Severity of Outcomes: No significant

Top 5 Takeaways High Prevalence Among Binge Drinkers: During 2015–2019, 34.4% of Colorado adults who binge drank also used marijuana, compared to 9.9% of nondrinkers. Age and Gender Differences: The

Top 5 Takeaways Lower Vaccine Effectiveness: The effectiveness of mRNA vaccines against COVID-19-associated hospitalization was lower among immunocompromised adults (77%) compared to immunocompetent adults (90%). Variation Among Subgroups: Vaccine effectiveness

Top 5 Takeaways Additional Primary Dose for Immunocompromised: ACIP recommends an additional mRNA COVID-19 vaccine dose for moderately to severely immunocompromised individuals. Booster Dose Recommendations: ACIP recommends a COVID-19 vaccine

Top 5 Takeaways Higher Odds of COVID-19 in Previously Infected: Unvaccinated adults with previous SARS-CoV-2 infection had 5.49 times higher odds of laboratory-confirmed COVID-19 compared to fully vaccinated individuals without