Top 5 Takeaways Vaccine Effectiveness Decline: The overall age-adjusted vaccine effectiveness (VE) against new COVID-19 cases declined from 91.8% to 75.0% during May 3–July 25, 2021. Stable Hospitalization Protection: VE

Top 5 Takeaways Emerging Substance: Xylazine, a veterinary tranquilizer, is increasingly found in drug overdose deaths in Connecticut. Combination with Fentanyl: Nearly all xylazine-positive deaths also involved fentanyl, highlighting a

Top 5 Takeaways High Vaccine Effectiveness: COVID-19 mRNA vaccines were 86.8% effective in preventing COVID-19–associated hospitalization among U.S. veterans. Effectiveness Across Variants: The effectiveness remained high during both pre-Delta (84.1%)

Top 5 Takeaways High Overall Vaccine Effectiveness: COVID-19 vaccines showed high effectiveness against hospitalization (86%) and emergency department/urgent care (ED/UC) encounters (82%) during the Delta variant predominance. Age-Related Differences: Vaccine

Top 5 Takeaways Vaccine Effectiveness: The study found a potential decline in vaccine protection against confirmed SARS-CoV-2 infection but continued strong protection against COVID-19–associated hospitalization and death. Impact of Delta

Top 5 Takeaways Increased BMI Rates: The rate of BMI increase nearly doubled during the COVID-19 pandemic compared to the prepandemic period. Higher Impact on Overweight and Obese: Persons aged

Top 5 Takeaways Disaggregated Data Reveals Disparities: Disaggregating COVID-19 data by specific racial subgroups in Hawaii highlighted significant disparities in case and mortality rates among Native Hawaiian, Pacific Islander, and