Top 5 Takeaways Disaggregated Data Reveals Disparities: Disaggregating COVID-19 data by specific racial subgroups in Hawaii highlighted significant disparities in case and mortality rates among Native Hawaiian, Pacific Islander, and

Top 5 Takeaways High Attack Rate: 74% of incarcerated persons in two housing units were infected during the outbreak. Vaccination Impact: The attack rate was higher among unvaccinated persons (93%)

Top 5 Takeaways Full FDA Approval: The Pfizer-BioNTech COVID-19 vaccine, Comirnaty, received full FDA approval for use in persons aged ≥16 years on August 23, 2021. High Efficacy: Clinical trials

Top 5 Takeaways High Vaccine Effectiveness: Receiving 2 or 3 doses of an mRNA COVID-19 vaccine was associated with a 90% reduction in risk for COVID-19–associated invasive mechanical ventilation (IMV)

Top 5 Takeaways Higher Hospitalization Rates During Omicron: Weekly COVID-19–associated hospitalization rates peaked at 38.4 per 100,000 adults during Omicron predominance, compared to 15.5 during Delta predominance. Impact of Vaccination

Top 5 Takeaways Higher VE for Moderna: The Moderna vaccine showed a higher vaccine effectiveness (VE) of 93% against COVID-19 hospitalizations compared to Pfizer-BioNTech’s 88% and Janssen’s 71%. Decline in

Top 5 Takeaways Vaccine Effectiveness (VE) Variability: VE against COVID-19–associated emergency department/urgent care visits was 24% after 1 Janssen dose, 54% after 2 Janssen doses, 79% after 1 Janssen/1 mRNA

Top 5 Takeaways Significant Decrease in Infections: The incidence of infections caused by enteric pathogens decreased by 26% in 2020 compared to 2017–2019. Impact of COVID-19 Interventions: Public health measures

Top 5 Takeaways Higher Prevalence Among Sexual Minority Women: Sexual minority women, including those identifying as bisexual or lesbian, report significantly higher rates of nonvoluntary or forced sex compared to