Top 5 Takeaways Full FDA Approval: On January 31, 2022, the FDA granted full approval to the Moderna COVID-19 vaccine for individuals aged ≥18 years. ACIP Recommendation: On February 4,

Top 5 Takeaways Vaccine Effectiveness Decline: The overall age-adjusted vaccine effectiveness (VE) against new COVID-19 cases declined from 91.8% to 75.0% during May 3–July 25, 2021. Stable Hospitalization Protection: VE

Top 5 Takeaways Emerging Substance: Xylazine, a veterinary tranquilizer, is increasingly found in drug overdose deaths in Connecticut. Combination with Fentanyl: Nearly all xylazine-positive deaths also involved fentanyl, highlighting a

Top 5 Takeaways High Adverse Event Rate: 91.4% of patients reported experiencing at least one adverse event during treatment with nifurtimox. Demographic Concentration: Most patients were adults aged ≥18 years