Top 5 Takeaways High Hospitalization Rates: 77.9% of children and adolescents hospitalized during the study period were admitted for acute COVID-19. Viral Coinfections: Approximately one third of children under 5

Top 5 Takeaways High Vaccine Effectiveness: The Pfizer-BioNTech vaccine showed 92% effectiveness in preventing SARS-CoV-2 infection among adolescents aged 12–17 years under real-world conditions. Study Design: A prospective cohort study

Top 5 Takeaways Common Reactions: Local and systemic reactions were frequently reported in children aged 5–11 years after Pfizer-BioNTech COVID-19 vaccination, especially after the second dose. Nonserious Events: Approximately 97.6%

Top 5 Takeaways COVID-19 Vaccination Safety: COVID-19 vaccination during pregnancy was not associated with an increased risk of preterm birth or small-for-gestational-age (SGA) at birth. Large Cohort Study: The study