Top 5 Takeaways

1. New and Updated Vaccine Recommendations: The 2024 schedule includes changes for respiratory syncytial virus (RSV), influenza, COVID-19, inactivated poliovirus vaccine (IPV), Mpox vaccine, and meningococcal vaccines.
2. Removal and Addition of Vaccines: MenACWY-D (Menactra) was removed due to discontinuation in the U.S., and Mpox (Jynneos), pentavalent meningococcal vaccine, and RSV vaccines were added.
3. COVID-19 Vaccine Updates: All adults are now recommended to receive at least one dose of the updated (2023–2024 Formula) COVID-19 vaccine, with specific guidance based on various factors.
4. Special Focus on RSV Vaccination: RSV vaccination recommendations include seasonal administration during pregnancy and shared clinical decision-making for adults aged ≥60 years.
5. Harmonization and Clarity in Vaccine Notes: Efforts were made to align language with the child and adolescent schedule and to provide clear guidance for each vaccine.

Original Article Author and Citation

Corresponding Author

Neil Murthy, nmurthy@cdc.gov

Suggested Citation

Murthy N, Wodi AP, McNally VV, Daley MF, Cineas S. Advisory Committee on Immunization Practices Recommended Immunization Schedule for Adults Aged 19 Years or Older — United States, 2024. MMWR Morb Mortal Wkly Rep 2024;73:11–15. DOI: http://dx.doi.org/10.15585/mmwr.mm7301a3.

Summary

The 2024 immunization schedule for adults has several key changes, including new and updated recommendations for several vaccines like RSV, influenza, COVID-19, IPV, Mpox, and meningococcal vaccines. Important modifications include the removal of MenACWY-D (Menactra) and the addition of vaccines like Mpox (Jynneos), pentavalent meningococcal vaccine, and RSV vaccines. Special attention is given to the COVID-19 vaccine, recommending at least one dose of the updated formula for all adults, and to RSV vaccination, especially during pregnancy and for older adults.

Methods

ACIP’s recommendations are based on thorough reviews of vaccine-related data, including epidemiology, efficacy, safety, and economic analyses. The schedule is approved by various health organizations and is intended to assist health care providers in implementing current vaccination recommendations.

Discussion

Significant updates reflect evolving needs and scientific advances in adult immunization. Removal of certain vaccines is due to discontinuation or change in recommendations, and new additions are in response to emerging health concerns. The focus on RSV, especially for pregnant women and older adults, highlights the growing importance of this vaccine.

Conclusion

The 2024 adult immunization schedule incorporates several critical changes and updates, reflecting ongoing efforts to protect public health through vaccination. Health care providers should use this comprehensive and updated schedule as a guide for adult immunization practices.

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